Carpal Tunnel Syndrome

What is Carpal Tunnel Syndrome?

Carpal Tunnel Syndrome (CTS) is a condition caused by the compression of the median nerve as it travels through the carpal tunnel in the wrist. The median nerve is one of the main nerves of the hand and controls sensation in the thumb, index, middle, and part of the ring finger. The carpal tunnel is a narrow passageway made up of bones and ligaments at the base of the hand. When swelling or pressure occurs in this space, the nerve becomes compressed, resulting in the symptoms of carpal tunnel syndrome.

Carpal tunnel syndrome is the most common nerve compression syndrome, and while its exact cause is often unknown, it is thought to be related to swelling of the contents in the tunnel or thickening of the surrounding ligament. This condition affects people of all ages but is more common in women and older adults.

While carpal tunnel syndrome is generally classified as a single condition, it can vary in severity and chronicity:

  • Mild Carpal Tunnel Syndrome: Symptoms are intermittent and typically occur during specific activities or at night. Numbness and tingling are present, but pain is mild.
  • Moderate Carpal Tunnel Syndrome: Symptoms are more frequent, including numbness, tingling, and pain that may extend into the forearm. Muscle weakness may be evident.
  • Severe Carpal Tunnel Syndrome: Symptoms are persistent, with constant numbness, loss of sensation, and noticeable muscle weakness, particularly in the thumb. Daily activities, such as gripping objects or buttoning clothing, become difficult.

While the cause of carpal tunnel syndrome is often unknown, a variety of factors can contribute to the development of the condition:

  • Repetitive hand or wrist movements: Activities that involve repetitive flexion or extension of the wrist, such as typing or using vibrating tools, can increase the risk.
  • Injury or trauma: Fractures, sprains, or dislocations in the wrist may result in swelling that compresses the median nerve.
  • Medical conditions: Certain conditions, such as arthritis, diabetes, obesity, and hypothyroidism, can increase the risk of developing carpal tunnel syndrome due to inflammation or fluid retention.
  • Hormonal changes: Pregnancy and menopause are associated with higher incidences of carpal tunnel syndrome due to hormonal fluctuations that can cause swelling in the wrist.
  • Age: The risk increases with age, and older individuals are more prone to developing carpal tunnel syndrome.

The most common symptoms of carpal tunnel syndrome include:

  • Numbness and tingling in the thumb, index, middle, and part of the ring finger, often occurring during activities that involve prolonged wrist flexion or extension.
  • Pain or discomfort in the hand and wrist, which may radiate up into the forearm.
  • Weakness in the hand, particularly affecting the thumb and making it difficult to perform fine motor tasks such as buttoning a shirt.
  • Waking at night due to numbness or pain, often relieved by shaking or hanging the hand over the side of the bed.
  • Reproduction of symptoms with pressure over the nerve or flexing the wrist. 
  • Electric shock like sensation when tapping over the nerve.
  • Loss of muscle mass at the base of the thumb (thenar muscle wasting) in severe cases.

Wrist Anatomy

The carpal tunnel is a narrow passageway located at the base of the hand, formed by the carpal bones on one side and the transverse carpal ligament on the other. It houses the median nerve and nine tendons that control finger movement. When any of the structures within the tunnel become swollen or irritated, the median nerve can be compressed, leading to the characteristic symptoms of carpal tunnel syndrome.

The median nerve controls sensation in the thumb, index, and middle fingers and is responsible for the movement of the muscles at the base of the thumb. Compression of this nerve can lead to the symptoms of carpal tunnel syndrome, which can range from mild tingling to severe muscle weakness and pain.

"OpenStax AnatPhys fig.8.9 - The Carpal Tunnel - English labels" by OpenStax, license: CC BY. Source: book 'Anatomy and Physiology', https://openstax.org/details/books/anatomy-and-physiology.

Treatment & Surgery Options

Non-surgical treatment is often the first approach for managing carpal tunnel syndrome, especially when symptoms are mild or intermittent. Common non-surgical options include:

  • Wrist Splinting: A splint holds the wrist in a neutral position to prevent further compression of the median nerve. Splints are often worn at night or during activities that exacerbate symptoms.
  • Steroid Injections: Corticosteroid injections can help reduce inflammation and swelling within the carpal tunnel, providing temporary relief. These injections are most effective in cases where symptoms have been present for less than a year, with a success rate of around 80%.
  • Activity Modification: Reducing repetitive wrist movements or adjusting hand positions during tasks can help alleviate symptoms. Ergonomic adjustments in the workplace may also reduce strain on the wrist.
  • Treating Underlying Conditions: Addressing medical conditions such as arthritis, diabetes, or hypothyroidism may help improve symptoms of carpal tunnel syndrome.

When non-surgical treatments fail to provide relief, or if symptoms worsen, surgical intervention may be necessary. Surgery for carpal tunnel syndrome aims to relieve pressure on the median nerve by releasing the transverse carpal ligament. Surgical options include:

  • Open Carpal Tunnel Release: In this procedure, a small incision is made in the palm of the hand to access and release the transverse carpal ligament, relieving pressure on the median nerve. This method is highly effective, and most patients experience significant symptom relief.
  • Endoscopic Carpal Tunnel Release: A minimally invasive alternative, this procedure involves using a small camera (endoscope) to guide the release of the transverse carpal ligament through a small incision. This method typically results in a quicker recovery and less scarring.

Both procedures are usually performed as day surgery under local anaesthetic, with patients returning home the same day. Recovery typically involves wearing a soft dressing and avoiding heavy lifting for six weeks. Light activities, such as using the hand for basic tasks, can be resumed immediately after surgery, and sutures are removed after two weeks.


Most patients experience significant relief following surgery, with a gradual return to full hand function. While recovery times vary, most individuals regain strength and sensation within several weeks to months, though it may take longer for severe cases. In some instances, if carpal tunnel syndrome has caused permanent nerve damage, complete recovery may not be possible.

Downloadable info sheets related to Carpal Tunnel Syndrome

These notes from OrthoSport Victoria are for educational purposes only and are not to be used as medical advice. Please seek the advice of your specific surgeon or other health care provider with any questions regarding medical conditions and treatment.

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